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New CG2 paper on Rheumatoid Arthritis Metabolism

10/23/2016

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Our group's latest paper is a bit out of the ordinary.
In a collaboration with the labs of George Kollias at BSRC "Fleming" and Georgios Theodoridis at the AUTH we have just published an analysis of the metabolic profile of an animal model of Rheumatoid Arthritis.
Our paper, titled: "Targeted metabolic profiling of the Tg197 mouse model reveals itaconic acid as a marker of Rheumatoid Arthritis", published in the Journal of Proteome Research, has revealed the importance of new, only recently reported metabolite called itaconic acid. Our group was involved in both the overall analysis of metabolite profiles, their linking with gene expression profiles, while we also had the chance to remember our past in Biochemistry in establishing the link between itaconic acid production and the disruption of the TCA cycle.

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