Our group has a new paper out in the latest issue of Computational Biology and Chemistry, a journal specializing in topics related to sequence analysis and complexity. The article entitled "Menzerath-Altmann law in mammalian exons reflects the dynamics of gene structure evolution" forms part of a special collective volume dedicated to the "Complexity of the Genome".
The main focus of our work is the existence of a linguistics law called "Menzerath-Altmann" in the gene structure. According to this law, one may expect that in genes with fewer exons, the mean size of these exons will tend to be greater. Although this property has already been reported by others (see e.g. here) we were able to provide a solid link with the dynamic process of exon evolution.
You can get a glimpse of the paper at the Publications page, while a full-text version is available upon request via e-mail.
The main focus of our work is the existence of a linguistics law called "Menzerath-Altmann" in the gene structure. According to this law, one may expect that in genes with fewer exons, the mean size of these exons will tend to be greater. Although this property has already been reported by others (see e.g. here) we were able to provide a solid link with the dynamic process of exon evolution.
You can get a glimpse of the paper at the Publications page, while a full-text version is available upon request via e-mail.
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